A minichromosome of LGVI from crossing two quasi-terminal reciprocal translocations

Meiotic behaviour of two human reciprocal translocations.

The meiotic behaviour of two male human reciprocal translocations is described. One patient had an unbalanced son and a chain configuration. The second had a stillborn child and a ring corresponding to an adjacent I segregation. The meiotic behaviour of chromosomal rearrangements must be investigated for proper genetic counselling.

Meiosis in two human reciprocal translocations.

Analysis of meiotic chromosomes from two human male translocation heterozygotes is reported. One had total sterility after maturation arrest and chain configurations at meiosis, and the second had a abnormal children who were presumed to be genetically unbalanced.

Reciprocal chromosome translocations: analysis of two mutants by interactive computer.

Two reciprocal translocations associated with microcephaly and retardation.

The first case is reported of a karyotype containing two apparently unrelated reciprocal translocations, involving chromosomes 1, 2, 5, and 7. It is suggested that the patient's psychomotor retardation and microcephaly may be the result of the loss of a small amount of chromosomal material accompanying these translocations.

Effect of Reciprocal Translocations on Phenotypic Abnormalities

The chromosomal disorders make a significant contribution to human mortality and morbidity. Karyotyping allows the identification of various chromosomes involved in a rearrangement. Chromosomal aberrations occur in approximately 1 in 200 live – born infants and the incidence of reciprocal translocations (rcpts) occur as 1/ 500 live births. Balanced reciprocal translocations can lead to a variet...